Occasional exposure isn’t going to do much. Some people even use kerosene (diesel) can be used to wash some things off your hands. But you want to avoid it when possible.
Another reason I hate the EPA “safety” gas can nozzles. Because I’ve never felt more safe than when I’m covered in gasoline.
Also for people thinking that this will block the functions that your existing one has integrated with the vehicle, you can get something like iDatalink Maestro to translate things. As long as it’s compatible with your car and the head unit is compatible with the Maestro then you can access existing functions.